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sa mssa reference strain atcc 25923  (ATCC)


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    ATCC sa mssa reference strain atcc 25923
    Sa Mssa Reference Strain Atcc 25923, supplied by ATCC, used in various techniques. Bioz Stars score: 98/100, based on 1070 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/mssa+reference+strain+atcc+25923/Staphylococcus+aureus%3B+subsp%2E+aureus/pm41692867-42-28-32
    Average 98 stars, based on 1070 article reviews
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    In Vivo:

    Article Title: Hit-to-Lead Identification and Validation of a Triaromatic Pleuromutilin Antibiotic Candidate.
    Article Snippet: Herein, we report the hit-to-lead identification of a drug-like pleuromutilin conjugate 16, based on a triaromatic hit reported in 2020.. The lead arose as the clear candidate from a hitoptimization campaign in which Gram-positive antibacterial activity, solubility, and P-gp affinity were optimized.. Conjugate 16 was extensively evaluated for its in vitro ADMET performance which, apart from solubility, was overall on par with lefamulin.

    Infection:

    Article Title: Hit-to-Lead Identification and Validation of a Triaromatic Pleuromutilin Antibiotic Candidate.
    Article Snippet: Herein, we report the hit-to-lead identification of a drug-like pleuromutilin conjugate 16, based on a triaromatic hit reported in 2020.. The lead arose as the clear candidate from a hitoptimization campaign in which Gram-positive antibacterial activity, solubility, and P-gp affinity were optimized.. Conjugate 16 was extensively evaluated for its in vitro ADMET performance which, apart from solubility, was overall on par with lefamulin.



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    A single-nucleotide polymorphism-based phylogenetic tree of methicillin resistance-lacking mec (MRLM) strains of Staphylococcus aureus . The whole genome sequences of all 13 strains analysed in this study (in red) were examined alongside those of 150 published MRLM strains, , downloaded from the NCBI database. The following MSSA genome sequences were also included: seven reference strains <t>ATCC</t> <t>25923</t> <t>(ST243/CC30,</t> <t>CP009361.1),</t> ATCC 29213 (ST5, GCA_001267715.2), ATCC 12600 (ST8, GCA_006094915.1), ATCC 9144 (ST30, GCA_900457695.1), NCTC 8325 (ST8, GCA_000013425.1), MSSA476 (ST1, GCA_000011525.1) and MSSA6850 (ST50, GCA_000462955.1), and eight previously reported clinical MSSA strains 10-00598 (ST22, GCA_028076695.1), 15-02736 (ST291, GCA_028082935.1), 16-01080 (ST45, GCA_028080235.1), 16-02665 (ST25, GCA_028075835.1), 18-01695 (ST398, GCA_028081975.1), 18-01787 (ST5, GCA_028081295.1), 19-00515 (ST15, GCA_028081935.1), and C00012754 (ST20, ERR418969). , Sequence types (STs) (inner ring), clonal complexes (CCs) (middle ring) and spa types (outer ring) are annotated. The tree scale indicates the number of substitutions per genome.
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    reference mssa strain atcc 25923  (ATCC)
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    ATCC reference mssa strain atcc 25923
    A single-nucleotide polymorphism-based phylogenetic tree of methicillin resistance-lacking mec (MRLM) strains of Staphylococcus aureus . The whole genome sequences of all 13 strains analysed in this study (in red) were examined alongside those of 150 published MRLM strains, , downloaded from the NCBI database. The following MSSA genome sequences were also included: seven reference strains <t>ATCC</t> <t>25923</t> <t>(ST243/CC30,</t> <t>CP009361.1),</t> ATCC 29213 (ST5, GCA_001267715.2), ATCC 12600 (ST8, GCA_006094915.1), ATCC 9144 (ST30, GCA_900457695.1), NCTC 8325 (ST8, GCA_000013425.1), MSSA476 (ST1, GCA_000011525.1) and MSSA6850 (ST50, GCA_000462955.1), and eight previously reported clinical MSSA strains 10-00598 (ST22, GCA_028076695.1), 15-02736 (ST291, GCA_028082935.1), 16-01080 (ST45, GCA_028080235.1), 16-02665 (ST25, GCA_028075835.1), 18-01695 (ST398, GCA_028081975.1), 18-01787 (ST5, GCA_028081295.1), 19-00515 (ST15, GCA_028081935.1), and C00012754 (ST20, ERR418969). , Sequence types (STs) (inner ring), clonal complexes (CCs) (middle ring) and spa types (outer ring) are annotated. The tree scale indicates the number of substitutions per genome.
    Reference Mssa Strain Atcc 25923, supplied by ATCC, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    ATCC reference strains atcc 25923 mssa
    A single-nucleotide polymorphism-based phylogenetic tree of methicillin resistance-lacking mec (MRLM) strains of Staphylococcus aureus . The whole genome sequences of all 13 strains analysed in this study (in red) were examined alongside those of 150 published MRLM strains, , downloaded from the NCBI database. The following MSSA genome sequences were also included: seven reference strains <t>ATCC</t> <t>25923</t> <t>(ST243/CC30,</t> <t>CP009361.1),</t> ATCC 29213 (ST5, GCA_001267715.2), ATCC 12600 (ST8, GCA_006094915.1), ATCC 9144 (ST30, GCA_900457695.1), NCTC 8325 (ST8, GCA_000013425.1), MSSA476 (ST1, GCA_000011525.1) and MSSA6850 (ST50, GCA_000462955.1), and eight previously reported clinical MSSA strains 10-00598 (ST22, GCA_028076695.1), 15-02736 (ST291, GCA_028082935.1), 16-01080 (ST45, GCA_028080235.1), 16-02665 (ST25, GCA_028075835.1), 18-01695 (ST398, GCA_028081975.1), 18-01787 (ST5, GCA_028081295.1), 19-00515 (ST15, GCA_028081935.1), and C00012754 (ST20, ERR418969). , Sequence types (STs) (inner ring), clonal complexes (CCs) (middle ring) and spa types (outer ring) are annotated. The tree scale indicates the number of substitutions per genome.
    Reference Strains Atcc 25923 Mssa, supplied by ATCC, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    A single-nucleotide polymorphism-based phylogenetic tree of methicillin resistance-lacking mec (MRLM) strains of Staphylococcus aureus . The whole genome sequences of all 13 strains analysed in this study (in red) were examined alongside those of 150 published MRLM strains, , downloaded from the NCBI database. The following MSSA genome sequences were also included: seven reference strains ATCC 25923 (ST243/CC30, CP009361.1), ATCC 29213 (ST5, GCA_001267715.2), ATCC 12600 (ST8, GCA_006094915.1), ATCC 9144 (ST30, GCA_900457695.1), NCTC 8325 (ST8, GCA_000013425.1), MSSA476 (ST1, GCA_000011525.1) and MSSA6850 (ST50, GCA_000462955.1), and eight previously reported clinical MSSA strains 10-00598 (ST22, GCA_028076695.1), 15-02736 (ST291, GCA_028082935.1), 16-01080 (ST45, GCA_028080235.1), 16-02665 (ST25, GCA_028075835.1), 18-01695 (ST398, GCA_028081975.1), 18-01787 (ST5, GCA_028081295.1), 19-00515 (ST15, GCA_028081935.1), and C00012754 (ST20, ERR418969). , Sequence types (STs) (inner ring), clonal complexes (CCs) (middle ring) and spa types (outer ring) are annotated. The tree scale indicates the number of substitutions per genome.

    Journal: JAC-Antimicrobial Resistance

    Article Title: Genetic and clinical landscape of methicillin-resistant Staphylococcus aureus isolates lacking the mec gene, in Japan

    doi: 10.1093/jacamr/dlag008

    Figure Lengend Snippet: A single-nucleotide polymorphism-based phylogenetic tree of methicillin resistance-lacking mec (MRLM) strains of Staphylococcus aureus . The whole genome sequences of all 13 strains analysed in this study (in red) were examined alongside those of 150 published MRLM strains, , downloaded from the NCBI database. The following MSSA genome sequences were also included: seven reference strains ATCC 25923 (ST243/CC30, CP009361.1), ATCC 29213 (ST5, GCA_001267715.2), ATCC 12600 (ST8, GCA_006094915.1), ATCC 9144 (ST30, GCA_900457695.1), NCTC 8325 (ST8, GCA_000013425.1), MSSA476 (ST1, GCA_000011525.1) and MSSA6850 (ST50, GCA_000462955.1), and eight previously reported clinical MSSA strains 10-00598 (ST22, GCA_028076695.1), 15-02736 (ST291, GCA_028082935.1), 16-01080 (ST45, GCA_028080235.1), 16-02665 (ST25, GCA_028075835.1), 18-01695 (ST398, GCA_028081975.1), 18-01787 (ST5, GCA_028081295.1), 19-00515 (ST15, GCA_028081935.1), and C00012754 (ST20, ERR418969). , Sequence types (STs) (inner ring), clonal complexes (CCs) (middle ring) and spa types (outer ring) are annotated. The tree scale indicates the number of substitutions per genome.

    Article Snippet: A comparative analysis of the nucleotide sequences or deduced amino acid sequences extracted from 13 MRLMs with those from the MSSA reference strain ATCC 25923 (ST243/CC30, CP009361.1) was conducted to identify mutations in the pbp4 promoter and amino acid substitutions in PBPs 1-4, GdpP, YjbH and AcrB.

    Techniques: Sequencing